| Drug | Condition | Usage | Dosage | Units |
|---|---|---|---|---|
| Aminophylline | (CHF with bronchoconstriction) | 4 - 8 mg/kg SC, IM, or IV.1 | - | mg |
| Atropine sulfate | (bradycardia) | 0.02 - 0.04 mg/kg SC, IV or IM.1 | - | mg |
| Atropine sulfate | (cholinergic toxicity) | 0.2 - 0.5 mg/kg;1/4 of the dose IV and the remainder IM or SC.1 | - | mg |
| Buprenorphine | (analgesic) | 0.01 - 0.03 mg/kg IM, IV, buccal1 | - | mg |
| Calcium gluconate | (hypocalcemia) | 94 - 140 mg/kg slowly IV to effect.1 | - | mg |
| Crystalloid fluids | (maintenance rate) | 2.5 mL/kg/hr CRI2 | mL | |
| Crystalloid fluids | (shock rate) | 60 - 70 mL/kg IV2 | - | mL |
| Dexamethasone sodium phosphate | (feline asthma) | 1 mg/kg IV.1 | mg | |
| Dexamethasone sodium phosphate | (shock or spinal injury) | 2.2 - 4.4 mg/kg IV.2 | - | mg |
| Dextran 70 | (colloid volume expansion) | 10 mL/kg/day as a slow (30 minute) bolus or CRI.1 | mL | |
| Diazepam | (seizure) | 0.5 - 1 mg/kg IV.1 | - | mg |
| Digoxin | (digitalization) | 0.005 mg/kg (lean body weight) divided between 3 doses (1/2 the dose initially, then 1/4 60 minutes later, then the remainder 60 minutes later if necessary)1 | mg | |
| Dobutamine | (inotrope) | 1 - 3 mcg/kg/min IV CRI1 | - | mcg |
| Doxapram | (respiratory stimulant) | 5 - 10 mg/kg IV2 | - | mg |
| Epinephrine | (anaphylaxis / bronchoconstriction) | 0.01 - 0.02 mg/kg IV1 | - | mg |
| Epinephrine | (anaphylaxis / bronchoconstriction) | 0.02 mg/kg IV, IM, SC, or IT.1 | mg | |
| Epinephrine | (asystole) | 0.05 - 0.5 mg of 1:10,000 solution IV or IT1 | - | mg |
| Epinephrine | (asystole) | 0.0005 - 0.005 mg/kg IC.1 | - | mg |
| Fentanyl (injectable) | (analgesia) | 1 - 3 mcg/kg IV loading dose; followed by 1 - 4 mcg/kg/hr CRI.1 | - INITIAL DOSE |
mcg |
| Furosemide | (severe pulmonary edema) | Up to 4.4 mg/kg IV or IM q 1-2 hours until respiration improves.1 | mg | |
| Glycopyrrolate | (bradyarrhythmias) | 0.005 - 0.01 mg/kg IV or IM1 | - | mg |
| Glycopyrrolate | (bradyarrhythmias) | 0.01 - 0.02 mg/kg SC.1 | - | mg |
| Hetastarch | (colloid volume expansion) | 1 - 2 mL/kg/hr; not to exceed 10 mL/kg in a 24 hour period.1 | - | mL |
| Hydromorphone | (analgesic) | 0.02 - 0.05 mg/kg IV, IM, or SC.1 | - | mg |
| Hypertonic saline (Sodium Chloride 7.5%) | (hypovolemic shock) | 2 - 8 mL/kg IV.2 | - | mL |
| Isoproterenol HCL | (sinoatrial arrest, sinus bradycardia, complete AV block) | 0.4 mg in 250 mL D5W drip slowly to effect1 | mg | |
| Lidocaine HCL (bolus/CRI) | (antiarrhythmic) | 0.25 - 0.5 mg/kg slowly IV.1 | - | mg |
| Mannitol | (cerebral edema/increased CSF) | 0.5 - 1.5 g/kg IV over 10 - 20 minutes.1 | - | g |
| Morphine sulfate (IM or SC) | (analgesic) | 0.2 - 0.5 mg/kg IM or SC.1 | - | mg |
| Morphine sulfate (IV) | (analgesic) | 0.02 - 0.1 mg/kg IV.1 | - | mg |
| Naloxone HCL | (opioid reversal) | 0.002 - 0.02 mg/kg IV or IM.1 | - | mg |
| Oxyglobin (hemoglobin glutamer) | (hemoglobin substitute) | 3 - 5 mL/kg slowly IV.2 | - | mL |
| Oxymorphone HCL | (analgesic) | 0.025 - 0.1 mg/kg IM, IV, or SC.1 | - | mg |
| Pentobarbital | (status epilepticus) | 3 to 15 mg/kg slowly IV to effect.1 | - | mg |
| Phenobarbital | (loading dose for seizures) | 16 - 20 mg/kg IV.1 | - | mg |
| Propofol | (refractory status epilepticus) | 0.1 - 0.6 mg/kg/min IV bolus or CRI.1 | - | mg |
| Sodium bicarbonate | (metabolic acidosis in cardiac arrest) | 1 mEq/kg IV initially, then 0.5 mEq/kg at 10 - 15 minute intervals during CPR.1 | INITIAL DOSE |
mEq |
| Aminophylline | (acute pulmonary edema and bronchoconstriction) | 4 - 8 mg/kg IV or IM1 | - | mg |
| Atropine sulfate | (bradycardia) | 0.02 - 0.04 mg/kg IV or IM.1 | - | mg |
| Atropine sulfate | (cholinergic toxicity) | 0.2 - 0.5 mg/kg; 1/4 of the dose IV and the remainder IM or SC.1 | - | mg |
| Buprenorphine | (analgesic) | 0.006 - 0.02 mg/kg IV, IM, or SC.1 | - | mg |
| Calcium gluconate | (hypocalcemia) | 94 - 140 mg/kg slowly IV to effect.1 | - | mg |
| Crystalloid fluids | (maintenance rate) | 2.5 mL/kg/hr CRI2 | mL | |
| Crystalloid fluids | (shock rate) | 90 mL/kg IV.2 | mL | |
| Dexamethasone sodium phosphate | (shock or spinal injury) | 2.2 - 4.4 mg/kg IV.2 | - | mg |
| Dextran 70 | (colloid volume expansion) | 20 mL/kg/day as a slow (30 minute) bolus or CRI.1 | mL | |
| Diazepam | (sedation/restraint) | 0.2 - 0.6 mg/kg IV.1 | - | mg |
| Diazepam | (seizure) | 0.5 - 1 mg/kg IV.1 | - | mg |
| Digoxin | (Rapid digitalization) | 0.0055 - 0.011 mg/kg IV q1h to effect.2 | - | mg |
| Dobutamine | (inotrope) | 1 - 10 mcg/kg/min IV CRI1 | - | mcg |
| Dopamine | (acute heart failure) | 1 - 10 mcg/kg/min CRI1 | - | mcg |
| Dopamine | (severe hypotension) | 1 - 3 mcg/kg/min CRI1 | - | mcg |
| Doxapram | (respiratory stimulant) | 5 - 10 mg/kg IV2 | - | mg |
| Epinephrine | (asystole) High Dose | 0.1 - 0.2 mg/kg IV or IO; repeat at 3 - 5 minute intervals.1 | - | mg |
| Epinephrine | (asystole) Low Dose | 0.01 - 0.02 mg/kg IV or IO; repeat at 3 - 5 minute intervals.1 | - | mg |
| Epinephrine | (bronchoconstriction) | 0.02 mg/kg IV, IM, SC, or IT.1 | mg | |
| Fentanyl (injectable) | (analgesia) | 2 - 5 mcg/kg IV loading dose; followed by 2 - 5 mcg/kg/hr CRI.1 | - INITIAL DOSE |
mcg |
| Furosemide | (severe pulmonary edema) | Up to 7.7 mg/kg IV or IM q 1-2 hours until respiration improves1 | mg | |
| Glycopyrrolate | (adjunctive therapy of bradyarrhythmias) | 0.011 mg/kg IV or IM.1 | mg | |
| Hetastarch | (colloid volume expansion) | 1 - 2 mL/kg/hr; not to exceed 20 mL/kg in a 24 hour period.1 | - | mL |
| Hydromorphone | (analgesic) | 0.05 - 0.2 mg/kg IV, IM, or SC.1 | - | mg |
| Hypertonic saline (Sodium Chloride 7.5%) | (hypovolemic shock) | 2 - 8 mL/kg IV.2 | - | mL |
| Isoproterenol HCL | (sinoatrial arrest, sinus bradycardia, complete AV block) | 0.4 mg in 250 mL D5W drip slowly to effect1 | mg | |
| Lidocaine HCL (bolus/CRI) | (antiarrhythmic) | 2 - 8 mg/kg slowly IV to effect; then 25 - 75 mcg/kg/min CRI, starting at a high dose and tapering when possible.1 | - INITIAL DOSE |
mg |
| Mannitol | (cerebral edema/increased CSF) | 0.5 - 1.5 g/kg IV over 10 - 20 minutes.1 | - | g |
| Morphine sulfate (IM or SC) | (analgesic) | 0.5 - 2.2 mg/kg IM or SC.1 | - | mg |
| Morphine sulfate (IV) | (analgesic) | 0.1 - 0.2 mg/kg IV.1 | - | mg |
| Naloxone HCL | (opioid reversal) | 0.002 - 0.02 mg/kg IV or IM.1 | - | mg |
| Oxyglobin (hemoglobin glutamer) | (hemoglobin substitute) | 10 - 30 mL/kg IV.2 | - | mL |
| Oxymorphone HCL | (analgesic) | 0.1 - 0.2 mg/kg IM, IV, or SC.1 | - | mg |
| Pentobarbital | (status epilepticus) | 3 to 15 mg/kg slowly IV to effect.1 | - | mg |
| Phenobarbital | (loading dose for seizures) | 16 - 20 mg/kg IV.1 | - | mg |
| Propofol | (refractory status epilepticus) | 0.1 - 0.6 mg/kg/min IV bolus or CRI.1 | - | mg |
| Sodium bicarbonate | (metabolic acidosis in cardiac arrest) | 1 mEq/kg IV initially, then 0.5 mEq/kg at 10 - 15 minute intervals during CPR.1 | INITIAL DOSE |
mEq |
| 1 | Plumb DC. Plumb's Veterinary Drug Handbook 6th edition. Blackwell Publishing, Ames, 2008. |
| 2 | Papich MG. Saunders Handbook of Veterinary Drugs 2nd edition. Saunders Elsevier, St. Louis, 2007. |
| CRI | Constant rate infusion |
| SC | Subcutaneous |
| IC | Intracardiac |
| IM | Intramuscular |
| IO | Intraosseous |
| IT | Intratracheal |
| IV | Intravenous |
